Our People

We have a team of dedicated researchers who are working on cutting edge research in the field of genome engineering.

Dr. Sivaprakash Ramalingam

Principal Investigator

Siva received his doctorate in Biotechnology from University of Madras, Chennai, India. After a brief stint at Pharma Company, Orchid Pharma Ltd, Chennai, as a Research Scientist, he pursued his post-doctoral studies in the laboratory of gene-editing pioneer and inventor of zinc finger nucleases Prof. Chandra at Johns Hopkins University School of Public Health, Baltimore, USA, with research focus on pluripotent stem cell engineering. During his post-doctoral research, he received MSCRF exploratory grant award from Maryland Stem Cell Research Fund in 2012 and then worked as a Junior Faculty at Johns Hopkins School of Public Health. He then returned to India with Ramalingaswami Fellowship Award from Department of Biotechnology and joined CSIR-IGIB in 2017 as a Senior Scientist.

Dr. Garima Thakur

Postdoctoral Fellow

Garima completed her PhD in Neurobiology (International PhD program of UZH/ETH) from University of Zurich in 2016. She is a part of a team that works on therapeutic correction of sickle cell disease mutation through gene editing. Currently, her research interests include finding small molecule drugs for fetal haemoglobin induction to ameliorate sickle cell disease/ beta thalassemia in patients. She looks forward to continue to work in the areas which can have more tangible and immediate impact on patients’ lives. When not doing experiments she likes to read, sketch and travel.

Sangam Giri Goswami

PhD Student

Sangam joined Dr. Sivaprakash Ramalingam’s Laboratory after completing his Masters in Biotechnology (M.Sc.) degree from Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh. His interest lies in the area of targeted genome editing to alleviate the symptoms in Sickle Cell Anemia patients. When not in lab, he focuses on his fitness training and likes to travel whenever possible.

Nupur Bhargava

PhD Student

Nupur finished her undergraduate studies at Miranda House, University of Delhi. She then went onto pursue her post-graduation in Biomedical Sciences at King’s College, London. Since early 2017, she has been working with Dr. Sivaprakash Ramlingam working on generation, and characterization of disease-specific iPSCs. In 2019,she started her PhD which aims at recapitulating beneficial mutations in disease model system for beta hemoglobinopathies. She likes to read in her free time.

Priya Thakur

PhD Student

Priya completed her undergraduate studies in Biotechnology from University of Mumbai. She moved to Baroda to complete her post-graduation in Medical Biotechnology from Maharaja Sayajirao University. She worked as a junior research fellow under Dr. Sanjay Gupta (ACTREC,) where her work focused on studying the roles of histone proteins in breast cancer. Since 2018 she joined Dr. Sivapraksh, working on therapeutic approaches for lysosomal storage disease using patient derived iPSCs. When not in lab she enjoys cooking and listening to music.

Pragya Gupta

PhD Student

Pragya joined Dr Siva's lab in December 2018. She completed her undergraduation from Sri Venkateswara college, University of Delhi and masters from department of genetics, University of Delhi. Her PhD research work mainly focuses on mechanisms involved in hemoglobin switching at different developmental stages.

Aarzoo Jindal

PhD Student

Aarzoo joined Dr. Ramalingam’s lab as a Ph.D student in September, 2020. She completed her Masters in Biotechnology from Savitribai Phule Pune University in 2020 and got her Bachelor of Science degree from MCMDAV college for Women, Panjab University in 2018. She comes from Chandigarh and likes to read, watch movies and travel in her free time.

Thulasi Priyadharshini

Research Fellow

Thulasi joined the lab as a research fellow in May 2019. Prior to that, she completed her Bachelor's in Biotechnology (B.Tech) at Rajalakshmi Engineering College, Anna University in 2016 and Master's in Biotechnology (M.Tech) at PSG College of Technology, Anna University in 2018. She is currently working on generating an adoptive CAR-T cell platform using iPScs and developing CRISPR based diagnostics for Beta Thalasemmia. In her free time, Thulasi likes to play badminton and read books.

Narendra Varma

Research Fellow

Narendra did his Bachelors in Biochemistry from Andhra University followed by Masters in Biochemistry and Molecular Biology from Pondicherry University. Soon after the graduation he worked as a research intern to understand the regulation of gene expression by Histone post translational modifications in gastric cancer, under the supervision of Dr. Sanjay Gupta, TMC-ACTREC. He is currently working as a JRF to investigate the molecular mechanisms associated with reactivation of fetal hemoglobin using genome editing tools. He finds motivation in books and likes to keep fit playing cricket and badminton.

Previous Members

Dr. Neelam Lohani

Postdoctoral Fellow

Neelam completed her PhD in Biochemistry from All India Institute of Medical Sciences, New Delhi, India in 2016. Presently she is pursuing her National Post-Doctoral fellowship awarded by SERB-Department of Science and Technology (Govt. of India). Her research in the lab focuses on reactivating fetal hemoglobin through CRISPR/Cas9 technology and develop a promising approach for treating β-hemoglobinopathies.

Shashank Jaitly

Research Fellow

Shashank did his bachelor’s in Biochemistry from Deshbandhu College, University of Delhi and his Masters in Biotechnology (M.Sc.) from Madurai Kamaraj University. His research interest lies in understanding the molecular aspects of reprogramming and using gene editing for therapeutic purposes. He is currently working on generation of patient specific iPSC lines and CRISPR mediated gene correction in β Thalassemia. In his free time he likes to follow Formula 1 and geopolitical news.