Publications

2022

  1. Bhargava N, Thakur P, Muruganandam TP, Jaitly S, Gupta P, Lohani N, Goswami SG, Saravanakumar V, Bhattacharya SK, Jain S, Ramalingam S (2022). Development of an efficient single-cell cloning and expansion strategy for genome-edited induced pluripotent stem cells. Mol Biol Rep. 49(8): 7887-7898.
  2. Thakur P, Gupta P, Bhargava N, Soni R, Varma Gottumukkala N, Goswami SG, Kharya G, Saravanakumar V, Gunda P, Jain S, Dass J, Aggarwal M, Ramalingam S. (2022). A Simple, Cost-Effective, and Extraction-Free Molecular Diagnostic Test for Sickle Cell Disease Using a Noninvasive Buccal Swab Specimen for a Limited-Resource Setting. Diagnostics. 21;12(7):1765.
  3. Sahel DK, Salman M, Azhar M, Goswami SG, Singh V, Dalela M, Mohanty S, Mittal A, Ramalingam S, Chitkara D (2022). Cationic lipopolymeric nanoplexes containing the CRISPR/Cas9 ribonucleoprotein for genome surgery. J Mater Chem B. doi: 10.1039/d2tb00645f.
  4. Yadav R, Devi S, Ramalingm S, Arya R (2022). Effect of GNE mutation on protein aggregate phenomenon: therapeutic challenges in ultra-rare GNE Myopathy. Int J Biochem Cell Biol. doi: 10.1016/j.biocel.2022.106258.
  5. Gupta P, Jaitly S, Thakur P, Goswami SG, Bhargava N, Ramalingam S (2022). Genome‐Editing Applications in Stem Cell Engineering and Regenerative Medicine. Genome Edit Drug Discov.  https://doi.org/10.1002/9781119671404.ch17.
  6. Kumari G, Rex DAB, Goswami S, Mukherjee S, Biswas S, Maurya P, Jain R, Garg S, Prasad TSK, Pati S, Ramalingam S, Mohandas N, Singh S (2022). Dynamic Palmitoylation of Red Cell Membrane Proteins Governs Susceptibility to Invasion by the Malaria Parasite, Plasmodium falciparum. ACS Infect Dis. doi: 10.1021/acsinfecdis.2c00199
  7. Dey SS, Ramalingam S, Taneja B (2022). A dual-plasmid based CRISPR/Cas9-mediated strategy enables targeted editing of pH regulatory gene paaC in a clinical isolate Trichophyton rubrum. J Fungi (accepted).
  8. Arumugam P, Chauhan M, Rajeev T, Chakraborty R, Bisht K, Madan M, Shankaran D, Ramalingam S, Gandotra S and Rao V (2022) The mitochondrial gene-CMPK2 functions as a rheostat for macrophage homeostasis. Front Immunol. 13:935710. doi: 10.3389/fimmu.2022.935710.

2021

  1. Sahana S, Sivadas A, Mangla M, Jain A, Bhoyar RM, Pandare K,..Mukerji M, Ramalingam S, Kumar B, Scaria V, Sivasubbu S (2021). Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes. Pharmacogenomics. doi: 10.2217/pgs-2021-0028.
  2. Jain A, Bhoyar RC, Pandhare K, Mishra A, Sharma D, Imran M, Senthivel V, , Soraisham R, Yadav R, Devi YS, Gupta A, Mukerji M, Ramalingam S, B K B, Scaria V, Sivasubbu S. Genetic epidemiology of autoinflammatory disease variants in Indian population from 1029 whole genomes. J Genet Eng Biotechnol. 2021 Dec 14;19(1):183.
  3. Kumar A, Ramalingam S, Rao DNR, Chandrasegaran S (2021). Genome Editing Revolution in Life Sciences. Resonance. DOI: https://doi.org/10.1007/s12045-021-1195-z
  4. Thakur P, Bhargava N, Jaitly S, Gupta P, Saroja, Padma P, Jain S, Bhattacharya S, Ramalingam S (2021). Establishment and characterization of induced pluripotent stem cell line (IGIBi002-A) from a β-thalassemia patient with IVS1-5 mutation by non-integrating reprogramming approach. Stem Cell Res. doi.org/10.1016/j.scr.2020.102124.

2020

  1. Jain A, Bhoyar RC, Pandhare K, Mishra A, Sharma D, Imran M, Senthivel V, Mukerji M, Ramalingam S, Kumar B, Scaria V, Sivasubbu S (2020). IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes. Nucleic Acids Res. doi: 10.1093/nar/gkaa923.
  2. Chakraborty D, Maiti S, Azhar M, Paul D, Acharya S, Phutela R, Hussain A, Sinha D, Kumar M, Rauthan R, Aich M, Sharma S, Sharma N, Mishra A, Jain S, Ray A, Ramalingam S (2020). Highly Precise ex vivo correction of sickle cell anemia mutation in patient cells using FnCas9. Mol Ther. 28(4). 105.
  3. Narasimhan I, Murali A, Subramanian K, Ramalingam S, Parameswaran S (2020). Autosomal dominant retinitis pigmentosa with toxic gain of function: Mechanisms and therapeutics. Eur J Ophthalmol. doi: 10.1177/1120672120957605.

2019

  1. Acharya S, Mishra A, Paul D, Ansari AH, Azhar M, Kumar M, Rauthan R, Sharma N, Aich M, Sinha D, Sharma S, Jain S, Ray A, Jain S, Ramalingam S, Maiti S, Chakraborty D. (2019) Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing. Proc Natl Acad Sci U S A. 15;116(42):20959-20968.
  2. Bajaj A, Methew S, Vellarikkal SK, Sivadas A, Bhoyar RC, Joshi K, Jain A, Verma, A, Jayaran A, Kumar RA, Seeralar AT, Gupta A, Achal K, The GuaRDIAN consortium, Ramalingam S,.Sharma YK, Brahmachari SK, Scaria A, Sivasubbu S (2019). Genomics of rare genetic diseases—experiences from India. Human Genomics. 13, 52.
  3. Ramalingam S and Thangaval S (2019) CRISPR-Cas9 probing of infectious disease and genetic disorders. The Ind J of Ped doi.org/10.1007/s12098-019-03037-9.
  4. Bhargava N, Jaitly S, Goswami S, Jain S, Chakarborty D, Ramalingam S (2019) Generation and characterization of induced pluripotent stem cells from a sickle cell anemia patient with homozygous β-globin mutation. Stem Cell Res 14;39:101484.

2018

  1. Lohani N, Bhargava N, Munshi A, Ramalingam S (2018) Pharmacological and molecular approaches for the treatment of β-hemoglobin disorders. J cell Physiol. 233 (6): 4563-4577.